A bright piece of news for fruit lovers: scientists have discovered that daily consumption of oranges is associated with a 20% reduction in the risk of depression. Could an ordinary orange really become an ally in the fight for a good mood? A new scientific work by specialists from Harvard Medical School and Massachusetts General Hospital makes us look at the humble southern fruit in a new way. Can a simple change in diet really have a noticeable effect on mental health?
Why scientists became interested in fruit and depression
Modern science is searching for ever new ways to support mental health, and the topic of nutrition has become one of the main focuses in this search. For decades, it was believed that food affects our bodies, but few people thought about its potential impact on mood and emotions. Historically, fruit was considered a source of vitamins, but hardly as a means of preventing psychological disorders.
Folk sayings like "An apple a day keeps the doctor away" have always emphasized the benefits of fruit, but now these ideas have scientific confirmation. As the authors of the new study note, testing familiar assumptions with modern methods opens up unexpected prospects for medicine.

How the study was conducted and who participated in it
The conclusion is based on data from the long-term Nurses’ Health Study II, which began in 1989. More than 100,000 women from different regions of the United States participate in this project, regularly reporting to scientists about their diet, lifestyle, medication use, and health status. Such a vast array of data makes it possible to draw reliable analytical conclusions and track possible links between diet and the development of various diseases.
In addition to surveys, scientists collected microbiological samples to analyze the composition of the gut microbiota using DNA sequencing. As a co-author of the study from Harvard Medical School, published in the journal Microbiome in 2024, emphasizes, "the large participant base and modern analytical methods allow us to speak of the high reliability of the results obtained." The scientists aimed to understand how certain foods, including oranges, might affect a person's psychological state.
How oranges affect the gut microbiota
The focus was on the microorganism Faecalibacterium prausnitzii—one of the key inhabitants of a healthy gut environment. Explaining its role, researchers compare the gut microbiota to a dense forest, where each type of bacteria performs its own function. Faecalibacterium prausnitzii supports immunity, reduces inflammation, and promotes the harmonious functioning of the gut. Analyses showed that those who regularly ate oranges and other citrus fruits had noticeably higher levels of F. prausnitzii than other participants.
At the same time, among people with low levels of this bacterium, depressive symptoms were more common. Based on related observations, specialists also note similar trends in men, although the main focus of the study was on the female audience. According to the authors, such results further confirm the universality of the link between diet and mental health.
How the connection between the gut and the brain affects mood
So what connects the microbiota and psychological state? The answer lies in the complex system of signals between the gut and the brain, known as the gut-brain axis. Here, neurotransmitters play a special role—biologically active substances that provide signal transmission between nerve cells. Serotonin and dopamine are the two main "mood hormones."
Such hormones are produced in the brain under the influence of many factors. In the modern world, a long list of these situations has been supplemented by various virtual entertainments—from watching short videos to mobile games. As well as the iGaming industry, which, judging by the data presented online, is growing year by year. As we learned here, IPL betting apps are becoming more and more numerous, indicating a growing number of users. And the reason for this is not only simplicity, but also the ability to quickly get pleasure in the form of dopamine and serotonin production.
But it is worth noting that serotonin and dopamine are produced not only in the brain, but also in the cells of the gut. The study shows that Faecalibacterium prausnitzii can stimulate their synthesis, affecting both digestive processes and emotional background. One can imagine the gut as a kind of orchestra, where each bacterium plays its own part, and a person's mood is the result of the harmony of this ensemble. Could it be that oranges are that very "fruit of joy" that citrus lovers have long suspected?
Limitations of the study and future prospects
Despite the inspiring results, scientists emphasize: this is an observational link, not a proven cause and effect. It is possible that a whole complex of factors affects mental health, and oranges are simply part of this "mosaic." According to experts, additional clinical trials involving different population groups are needed to finally confirm the benefits of fruit for the prevention of depression.
The study considered only part of the sample, and individual characteristics and accompanying conditions could have influenced the final data. As one of the authors notes, "oranges cannot replace professional treatment for depression, but they can become a useful element of overall health improvement." In the future, scientists plan to study how different dietary habits or other nutritional components may be related to mental state, and what mechanisms underlie this interaction.
Useful tips
So what should those who want to strengthen their psychological health do? Regular consumption of oranges and other fresh fruits can well become a pleasant and healthy habit. However, specialists recommend not to consider fruit as a universal remedy: according to them, a healthy diet is about variety, balance, and attention to the individual needs of the body.
In addition to nutrition, physical activity, adequate sleep, and timely seeking help from specialists in case of mood deterioration or the appearance of anxious symptoms are important. Maintaining good well-being is helped by a conscious approach to one's own health and a willingness to observe changes in condition. A simple orange really can bring joy, but self-care requires a comprehensive approach and regular attention.